Metal resistance sequences and transgenic plants

Overview

Information

Number: 5668294
Application: 08/427097
Filing date: 04/21/1995
Issue date: 09/16/1997
Inventor(s): Richard B. Meagher, Anne O. Summers

US Classification: 435/320.1; 435/468; 435/69.1; 536/23.2; 536/23.7; 536/24.1; 800/278; 800/287; 800/294; 800/298; 800/317

Citations

Edenspace Systems (1)

Number	Title	Issue Date
5364451	Phytoremediation of metals	1994/11/15

B & H Manufacturing (1)

Number	Title	Issue Date
5380381	Labeling machine with variable speed cutting head	1995/01/10

CELLECTIS (1)

Number	Title	Issue Date
4849355	Method of transferring genes into cells	1989/07/18

Abstract

Abstract

The present invention provides nucleic acid sequences encoding a metal ion resistance protein, which are expressible in plant cells. The metal resistance protein provides for the enzymatic reduction of metal ions including by not limited to divalent Cu, divalent mercury, trivalent gold, divalent cadmium, lead ions and monovalent silver ions. Transgenic plants which express these coding sequences exhibit increased resistance to metal ions in the environment as compared with plants which have not been so genetically modified. Transgenic plants which are resistant to organomercurials including alkylmercury compounds, among others, are provided by the further inclusion of plant-expressible organomercurial lyase coding sequences. Furthermore, these transgenic plants which have been genetically modified to express the metal resistance coding sequences of the present invention can participate in the bioremediation of metal contamination via the enzymatic reduction of metal ions. Transgenic plants resistant to organomercurials can further mediate remediation of alkylmercury compounds in the environment by causing the freeing of mercuric ions and the reduction of the ionic mercury to the less toxic elemental mercury.

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Referenced by

UNIVERSITY OF GEORGIA, THE (4)

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Genopsys (3)

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6630329	Random truncation and amplification of nucleic acid	2003/10/07
6319694	Random truncation and amplification of nucleic acid	2001/11/20
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bioMerieux (1)

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University of Guelph (1)

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Savannah River Nuclear Solutions, (1)

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Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
435	320.1	Emerging	Average	Seminal	Medium	Average	28.2
435	468	Emerging	Average	Seminal	Medium	Average	47.3
435	69.1	Emerging	Average	Seminal	Medium	Average	27.8
536	23.2	Emerging	Average	Seminal	Medium	Average	34.0
536	23.7	Emerging	Average	Seminal	Medium	Average	30.8
536	24.1	Emerging	Average	Seminal	Medium	Average	26.3
800	278	Emerging	Average	Seminal	Medium	Average	39.3
800	287	Emerging	Average	Seminal	Medium	Rapid	20.4
800	294	Emerging	Average	Seminal	Medium	Rapid	23.1
800	298	Emerging	Average	Seminal	Medium	Average	35.4
800	317	Emerging	Average	Seminal	Medium High	Slow	77.7