Anti-adhesion films and compositions for medical use

Overview

Information

Number
5580923
Application
08/403360
Filing date
03/14/1995
Issue date
12/03/1996
Inventor(s)
Jeffrey E. Yeung, George H. Chu, Frank A. DeLustro, Woonza M. Rhee
US Classification
523/105; 523/113; 525/54.1; 602/50; 602/52
View at USPTO

Citations

Koken Co. (1)
ANGIODEVICE INTERNATIONAL (1)
Dr. Karl Thomae (1)

Abstract

Abstract

Anti-adhesion films useful for the prevention of surgical adhesions are disclosed. These films comprise substrate materials (such as collagen) and hetero-bifunctional anti-adhesion binding agents, wherein the substrate material is covalently linked to receptive tissue within the body of a patient via the binding agent. Preferred binding agents comprise substrate-reactive and tissue-selective functional groups. Anti-adhesion compositions useful for the formation of such films are also disclosed.

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Tech Analysis

Class Subclass Type Reference Factor Citation Factor Strength Grant time Early grant (%)
523 105 Stable Average Seminal Medium High Average 27.8
523 113 Stable Average Seminal Medium High Rapid 23.8
525 54.1 Stable Average Seminal Medium High Average 27.6
602 50 Emerging Average Seminal Medium High Rapid 20.6
602 52 Stable Average Seminal Medium High Average 27.1