| Number | Title | Issue Date |
|---|---|---|
| 4704131 | Medical materials | 1987/11/03 |
| Number | Title | Issue Date |
|---|---|---|
| 5162430 | Collagen-polymer conjugates | 1992/11/10 |
| Number | Title | Issue Date |
|---|---|---|
| 5364622 | Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel | 1994/11/15 |
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|---|---|---|
| 5989215 | Fibrin delivery device and method for forming fibrin on a surface | 1999/11/23 |
| 6074663 | Method of using cross-linked fibrin material | 2000/06/13 |
| 6461325 | Fibrin delivery device and method for forming fibrin on a surface | 2002/10/08 |
| 7135027 | Devices and methods for mixing and extruding medically useful compositions | 2006/11/14 |
| 7135027 | Devices and methods for mixing and extruding medically useful compositions | 2006/11/14 |
| 7226657 | Element provided with a fibrin layer, preparation and use thereof | 2007/06/05 |
| 7766919 | Devices for mixing and extruding medically useful compositions | 2010/08/03 |
| 7766919 | Devices for mixing and extruding medically useful compositions | 2010/08/03 |
| 8092820 | Dry hemostatic compositions and methods for their preparation | 2012/01/10 |
| 8303981 | Fragmented polymeric compositions and methods for their use | 2012/11/06 |
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| 8357378 | Fragmented polymeric compositions and methods for their use | 2013/01/22 |
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| 8383141 | Dry hemostatic compositions and methods for their preparation | 2013/02/26 |
| 8383141 | Dry hemostatic compositions and methods for their preparation | 2013/02/26 |
| 8512729 | Fragmented polymeric compositions and methods for their use | 2013/08/20 |
| 8512729 | Fragmented polymeric compositions and methods for their use | 2013/08/20 |
| 8603511 | Fragmented polymeric compositions and methods for their use | 2013/12/10 |
| 8603511 | Fragmented polymeric compositions and methods for their use | 2013/12/10 |
| 8703122 | Method for directed cell in-growth and controlled tissue regeneration in spinal surgery | 2014/04/22 |
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| 8703170 | Hemostatic sponge | 2014/04/22 |
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| 8790698 | Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects | 2014/07/29 |
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| 8834864 | Methods for repairing and regenerating human dura mater | 2014/09/16 |
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| 8940335 | Process for making dry and stable hemostatic compositions | 2015/01/27 |
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| 9833541 | Hemostatic compositions | 2017/12/05 |
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| Number | Title | Issue Date |
|---|---|---|
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| 8367099 | Perforated fatty acid films | 2013/02/05 |
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| 7316704 | Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture | 2008/01/08 |
| 7335220 | Apparatus and methods for sealing a vascular puncture | 2008/02/26 |
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| 7985240 | Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture | 2011/07/26 |
| 7993367 | Apparatus and methods for sealing a vascular puncture | 2011/08/09 |
| 8002742 | Apparatus and methods for sealing a puncture in tissue | 2011/08/23 |
| 8029533 | Apparatus and methods for sealing a vascular puncture | 2011/10/04 |
| 8128654 | Apparatus and methods for sealing a vascular puncture | 2012/03/06 |
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| 8382797 | Methods for sealing a vascular puncture | 2013/02/26 |
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| 8394122 | Apparatus and methods for sealing a vascular puncture | 2013/03/12 |
| 8617204 | Apparatus and methods for sealing a vascular puncture | 2013/12/31 |
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| 8951283 | Apparatus and methods for sealing a vascular puncture | 2015/02/10 |
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| 9289195 | Auto-retraction apparatus and methods for sealing a vascular puncture | 2016/03/22 |
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| 10499893 | Apparatus and methods for sealing a vascular puncture | 2019/12/10 |
| 10595838 | Apparatus and methods for sealing a vascular puncture | 2020/03/24 |
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| Number | Title | Issue Date |
|---|---|---|
| 7331979 | Apparatus and methods for sealing a vascular puncture | 2008/02/19 |
| 9039735 | Apparatus and methods for sealing a vascular puncture | 2015/05/26 |
| 9107645 | Apparatus and methods for sealing a puncture in tissue | 2015/08/18 |
| 9757105 | Apparatus and methods for sealing a vascular puncture | 2017/09/12 |
| 9820728 | Apparatus and methods for sealing a vascular puncture | 2017/11/21 |
| 10149670 | Apparatus and methods for sealing a vascular puncture | 2018/12/11 |
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| 10314567 | Apparatus and methods for sealing a vascular puncture | 2019/06/11 |
| 10456124 | Apparatus and methods for sealing a vascular puncture | 2019/10/29 |
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| 11925337 | Apparatus and methods for sealing a vascular puncture | 2024/03/12 |
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| Number | Title | Issue Date |
|---|---|---|
| 6514534 | Methods for forming regional tissue adherent barriers and drug delivery systems | 2003/02/04 |
| 6818018 | In situ polymerizable hydrogels | 2004/11/16 |
| 7009034 | Biocompatible crosslinked polymers | 2006/03/07 |
| 7025990 | Methods for forming regional tissue adherent barriers and drug delivery systems | 2006/04/11 |
| 7332566 | Biocompatible crosslinked polymers with visualization agents | 2008/02/19 |
| 7347850 | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof | 2008/03/25 |
| 7592418 | Biocompatible crosslinked polymers with visualization agents | 2009/09/22 |
| 7648713 | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels | 2010/01/19 |
| 7780980 | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels | 2010/08/24 |
| 7790192 | Apparatus and methods for sealing a vascular puncture | 2010/09/07 |
| 8003705 | Biocompatible hydrogels made with small molecule precursors | 2011/08/23 |
| 8105622 | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels | 2012/01/31 |
| 8470362 | Methods for sealing a vascular puncture using a plug including unreactive precursors | 2013/06/25 |
| 8535705 | Biocompatible polymers and hydrogels and methods of use | 2013/09/17 |
| 8795709 | Superabsorbent, freeze dried hydrogels for medical applications | 2014/08/05 |
| 8852230 | Apparatus and methods for sealing a vascular puncture | 2014/10/07 |
| 8986730 | Methods for sealing a vascular puncture | 2015/03/24 |
| 9386969 | Methods for sealing a vascular puncture | 2016/07/12 |
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| 10940231 | Superabsorbent, freeze dried hydrogels for medical applications | 2021/03/09 |
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| Number | Title | Issue Date |
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| 9427309 | Soft tissue repair devices, systems, and methods | 2016/08/30 |
| 9629632 | Soft tissue repair devices, systems, and methods | 2017/04/25 |
| 9655625 | Soft tissue repair devices, systems, and methods | 2017/05/23 |
| 10219804 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2019/03/05 |
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| 10835241 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2020/11/17 |
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| 11944531 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2024/04/02 |
| 11957334 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2024/04/16 |
| 11980360 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2024/05/14 |
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| 12508019 | Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone | 2025/12/30 |
| Number | Title | Issue Date |
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| 6166130 | Method of using crosslinked polymer compositions in tissue treatment applications | 2000/12/26 |
| 6323278 | Method of making crosslinked polymer matrices in tissue treatment applications | 2001/11/27 |
| 6458889 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | 2002/10/01 |
| 6534591 | Cross-linked polymer compositions and methods for their use | 2003/03/18 |
| 6833408 | Methods for tissue repair using adhesive materials | 2004/12/21 |
| 6911496 | Composition for administration of a biologically active compound | 2005/06/28 |
| 6969400 | Synthetic implant with nonimmunogenicity coating | 2005/11/29 |
| 7883693 | Compositions and systems for forming crosslinked biomaterials and methods of preparation of use | 2011/02/08 |
| 7883694 | Method for preventing the formation of adhesions following surgery or injury | 2011/02/08 |
| 8067031 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | 2011/11/29 |
| 8197802 | Method for treating or inhibiting the formation of adhesions following surgery or injury | 2012/06/12 |
| 8377466 | Adhesive tissue repair patch | 2013/02/19 |
| 8460708 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | 2013/06/11 |
| 8481073 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use | 2013/07/09 |
| 8617584 | Adhesive tissue repair patch and collagen sheets | 2013/12/31 |
| Number | Title | Issue Date |
|---|---|---|
| 8372437 | Placental tissue grafts | 2013/02/12 |
| 8460715 | Placental tissue grafts | 2013/06/11 |
| 8460716 | Method for applying a label to a placental tissue graft | 2013/06/11 |
| 8597687 | Methods for determining the orientation of a tissue graft | 2013/12/03 |
| 8623421 | Placental graft | 2014/01/07 |
| 8709494 | Placental tissue grafts | 2014/04/29 |
| 9265800 | Placental tissue grafts | 2016/02/23 |
| 9265801 | Placental tissue grafts | 2016/02/23 |
| 9272005 | Placental tissue grafts | 2016/03/01 |
| 9433647 | Placental tissue grafts | 2016/09/06 |
| 9463207 | Placental tissue grafts | 2016/10/11 |
| 9572839 | Placental tissue grafts and methods of preparing and using the same | 2017/02/21 |
| 9956253 | Placental tissue grafts | 2018/05/01 |
| 10406259 | Placental tissue grafts and improved methods of preparing and using the same | 2019/09/10 |
| 11504449 | Placental tissue grafts and methods of preparing and using the same | 2022/11/22 |
| Number | Title | Issue Date |
|---|---|---|
| 11801324 | Method for preparing a haemostatic composition | 2023/10/31 |
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| 9265858 | Dry haemostatic composition | 2016/02/23 |
| 9533069 | Device for promotion of hemostasis and/or wound healing | 2017/01/03 |
| 9724078 | Vacuum expanded dry composition and syringe for retaining same | 2017/08/08 |
| 9999703 | Dry haemostatic composition | 2018/06/19 |
| 10111980 | Dry composition comprising an extrusion enhancer | 2018/10/30 |
| 10595837 | Vacuum expanded dry composition and syringe for retaining same | 2020/03/24 |
| 10653837 | Syringe for retaining and mixing first and second substances | 2020/05/19 |
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| 11046818 | Dry composition for use in haemostasis and wound healing | 2021/06/29 |
| 11103616 | Dry composition comprising an extrusion enhancer | 2021/08/31 |
| 11109849 | Pressurized container containing haemostatic paste | 2021/09/07 |
| Number | Title | Issue Date |
|---|---|---|
| 7208145 | Polymeric reagents comprising a ketone or a related functional group | 2007/04/24 |
| 7851565 | Stabilized polymeric thiol reagents | 2010/12/14 |
| 8217123 | Stabilized polymeric thiol reagents | 2012/07/10 |
| 8492488 | Stabilized polymeric thiol reagents | 2013/07/23 |
| 8765883 | Stabilized polymeric thiol reagents | 2014/07/01 |
| 8865149 | Polymeric reagents comprising a ketone or a related functional group | 2014/10/21 |
| 9308274 | Stabilized polymeric thiol reagents | 2016/04/12 |
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|---|---|---|
| 6150581 | Chitosan/alginate anti-adhesion barrier | 2000/11/21 |
| 8470355 | Mesh implant | 2013/06/25 |
| 9084602 | Buttress film with hemostatic action for surgical stapling apparatus | 2015/07/21 |
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| 9889230 | Hemostatic implant | 2018/02/13 |
| 10722224 | Medical device for wound closure and method of use | 2020/07/28 |
| 11382731 | Medical devices with sealing properties | 2022/07/12 |
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|---|---|---|
| 8324184 | Anti-adhesion composites and methods of use thereof | 2012/12/04 |
| 8852214 | System for tissue fixation to bone | 2014/10/07 |
| 8858577 | Tissue stabilization system | 2014/10/14 |
| 8945156 | Tissue fixation | 2015/02/03 |
| 9381019 | System for tissue fixation to bone | 2016/07/05 |
| 9451961 | Tissue stabilization system | 2016/09/27 |
| Number | Title | Issue Date |
|---|---|---|
| 7727547 | Tissue-adhesive formulations | 2010/06/01 |
| 8133336 | Tissue-adhesive materials | 2012/03/13 |
| 8133504 | Tissue-adhesive materials | 2012/03/13 |
| Number | Title | Issue Date |
|---|---|---|
| 9005609 | Hemostatic compositions containing sterile thrombin | 2015/04/14 |
| 11801324 | Method for preparing a haemostatic composition | 2023/10/31 |
| 12544483 | Method for preparing a haemostatic composition | 2026/02/10 |
| Number | Title | Issue Date |
|---|---|---|
| 7429241 | Dural graft and method of preparing the same | 2008/09/30 |
| 8039591 | Flowable collagen material for dural closure | 2011/10/18 |
| 8795710 | Collagen device and method of preparing the same | 2014/08/05 |
| Number | Title | Issue Date |
|---|---|---|
| 7151135 | Crosslinked polymer compositions | 2006/12/19 |
| 7176256 | Biocompatible crosslinked composition | 2007/02/13 |
| 9353218 | Kit for multifunctional compounds forming crosslinked biomaterials | 2016/05/31 |
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|---|---|---|
| 6180418 | Force discrimination assay | 2001/01/30 |
| 6180418 | Force discrimination assay | 2001/01/30 |
| Number | Title | Issue Date |
|---|---|---|
| 7758654 | Anti-adhesion device | 2010/07/20 |
| 8361164 | Anti-adhesion device | 2013/01/29 |
| Number | Title | Issue Date |
|---|---|---|
| 10549015 | Method for preparing an anti-adhesion barrier film | 2020/02/04 |
| 12070534 | Method for preparing an anti-adhesion barrier film | 2024/08/27 |
| Number | Title | Issue Date |
|---|---|---|
| 7785717 | Fluorescent ink compositions comprising functionalized fluorescent nanocrystals | 2010/08/31 |
| 8241765 | Fluorescent ink compositions comprising functionalized fluorescent nanocrystals | 2012/08/14 |
| Number | Title | Issue Date |
|---|---|---|
| 6280474 | Devices for tissue repair and methods for preparation and use thereof | 2001/08/28 |
| 7273896 | Compositions and methods of using a transient colorant | 2007/09/25 |
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|---|---|---|
| 5979446 | Removable fallopian tube plug and associated methods | 1999/11/09 |
| 6357443 | Removable fallopian tube plug and associated methods | 2002/03/19 |
| Number | Title | Issue Date |
|---|---|---|
| 9907882 | Demineralized bone matrix with improved osteoinductivity | 2018/03/06 |
| 10463763 | Demineralized bone matrix with improved osteoinductivity | 2019/11/05 |
| Number | Title | Issue Date |
|---|---|---|
| 6303112 | Enriched platelet wound healant | 2001/10/16 |
| Number | Title | Issue Date |
|---|---|---|
| 6623748 | Reverse phase connective tissue repair composition | 2003/09/23 |
| Number | Title | Issue Date |
|---|---|---|
| 6391939 | Collagenic material useful in particular for preventing post-operative adhesions | 2002/05/21 |
| Number | Title | Issue Date |
|---|---|---|
| 5977252 | Covalent modification of surfaces with polymers to increase biocompatibility | 1999/11/02 |
| Number | Title | Issue Date |
|---|---|---|
| 7311980 | Polyactive/polylactic acid coatings for an implantable device | 2007/12/25 |
| Number | Title | Issue Date |
|---|---|---|
| 7737214 | Adhesion preventive material | 2010/06/15 |
| Class | Subclass | Type | Reference Factor | Citation Factor | Strength | Grant time | Early grant (%) |
|---|---|---|---|---|---|---|---|
| 523 | 105 | Stable | Average | Seminal | Medium High | Average | 27.8 |
| 523 | 113 | Stable | Average | Seminal | Medium High | Rapid | 23.8 |
| 525 | 54.1 | Stable | Average | Seminal | Medium High | Average | 27.6 |
| 602 | 50 | Emerging | Average | Seminal | Medium High | Rapid | 20.6 |
| 602 | 52 | Stable | Average | Seminal | Medium High | Average | 27.1 |