Devices for tissue repair and methods for preparation and use thereof

Overview

Information

Number: 6083522
Application: 09/004550
Filing date: 01/08/1998
Issue date: 07/04/2000
Inventor(s): George H. Chu, Jeff E. Yeung, Jacqueline Anne Schroeder, Vivek N. Shenoy, Melissa K. C. Brown, James J. Cassidy, John Rice

US Classification: 424/423; 623/16.11; 623/21.15; 623/22.11; 623/23.75

Citations

Angiotech International (8)

Number	Title	Issue Date
5306500	Method of augmenting tissue with collagen-polymer conjugates	1994/04/26
5475052	Collagen-synthetic polymer matrices prepared using a multiple step reaction	1995/12/12
5446091	Collagen-polymer conjugates containing an ether linkage	1995/08/29
5413791	Collagen-polymer conjugates	1995/05/09
5376375	Method of augmenting tissue using collagen-polymer conjugates	1994/12/27
5328955	Collagen-polymer conjugates	1994/07/12
5110604	Processes for producing collagen matrixes and methods of using same	1992/05/05
5523348	Method of preparing collagen-polymer conjugates	1996/06/04

Cohesion Technologies (4)

Number	Title	Issue Date
4743229	Collagen/mineral mixing device and method	1988/05/10
4488911	Non-antigenic collagen and articles of manufacture	1984/12/18
4424208	Collagen implant material and method for augmenting soft tissue	1984/01/03
5428022	Composition of low type III content human placental collagen	1995/06/27

ALLERGAN (3)

Number	Title	Issue Date
5035715	Gamma irradiation of collagen/mineral mixtures	1991/07/30
4642117	Mechanically sheared collagen implant material and method	1987/02/10
4582640	Injectable cross-linked collagen implant material	1986/04/15

ANGIODEVICE INTERNATIONAL (3)

Number	Title	Issue Date
5324775	Biologically inert, biocompatible-polymer conjugates	1994/06/28
5304595	Collagen-polymer conjugates	1994/04/19
5162430	Collagen-polymer conjugates	1992/11/10

COLLAGEN (3)

Number	Title	Issue Date
4140537	Aqueous collagen composition	1979/02/20
4888366	Inductive collagen-based bone repair preparations	1989/12/19
4563350	Inductive collagen based bone repair preparations	1986/01/07

Vitaphore (1)

Number	Title	Issue Date
5322648	Process for forming shaped collagen devices	1994/06/21

Battelle Memorial Institute (1)

Number	Title	Issue Date
4544516	Collagen orientation	1985/10/01

bonutti skeletal innovations (1)

Number	Title	Issue Date
5718717	Suture anchor	1998/02/17

REGENTS OF THE UNIVERSITY OF MICHIGAN, THE (1)

Number	Title	Issue Date
5501706	Medical implant structure and method for using the same	1996/03/26

ANGIOTECH BIOMATERIALS CORP. (1)

Number	Title	Issue Date
4776890	Preparation of collagen hydroxyapatite matrix for bone repair	1988/10/11

VISION 2000 TECHNOLOGIES (1)

Number	Title	Issue Date
4164559	Collagen drug delivery device	1979/08/14

Nitta Gelatin (1)

Number	Title	Issue Date
4533358	Process for producing a shaped product of collagen by syneresis	1985/08/06

Neucoll (1)

Number	Title	Issue Date
4795467	Xenogeneic collagen/mineral preparations in bone repair	1989/01/03

basf beauty care solutions france sas (1)

Number	Title	Issue Date
4923380	Apparatus for the extrusion of collogen tubes	1990/05/08

Abstract

Abstract

Disclosed herein are uniformly shaped swellable devices comprising polymeric materials, as well as apparatuses and processes for their manufacture. In one embodiment, the present invention relates to load bearing implant devices for use in tissue repair. The implants consist of a resorbable, swellable implant body which is formed from a dehydrated crosslinked biocompatible polymer. As such, the implants are capable of swelling after insertion to become anchored in place. The implants function to enhance the structural integrity of the hard tissue into which they are placed, and thereby improve the load bearing capacity of such tissues. The implants are particularly well suited for use in attaching a second (hard or soft) tissue to the first (hard) tissue into which the implant is inserted. They may also be used as a site for attachment of a surgical device such as a screw, rod or pin.

Assignees with Similar Patents

Referenced by

P Tech, . (77)

Number	Title	Issue Date
8496657	Methods for utilizing vibratory energy to weld, stake and/or remove implants	2013/07/30
8617185	Fixation device	2013/12/31
8617208	Method of using ultrasonic vibration to secure body tissue with fastening element	2013/12/31
8747439	Method of using ultrasonic vibration to secure body tissue with fastening element	2014/06/10
9060767	Tissue fastener and methods for using same	2015/06/23
9067362	Method of using ultrasonic vibration to secure body tissue with fastening element	2015/06/30
9089323	Device and method for securing body tissue	2015/07/28
9138222	Method and device for securing body tissue	2015/09/22
9149281	Robotic system for engaging a fastener with body tissue	2015/10/06
9155544	Robotic systems and methods	2015/10/13
9173647	Tissue fixation system	2015/11/03
9173650	Methods and devices for trauma welding	2015/11/03
9192395	Robotic fastening system	2015/11/24
9226828	Devices and methods for stabilizing tissue and implants	2016/01/05
9271741	Robotic ultrasonic energy system	2016/03/01
9271766	Devices and methods for stabilizing tissue and implants	2016/03/01
9271779	Methods of using a robotic spine system	2016/03/01
9402668	Tissue fixation system and method	2016/08/02
9421005	Methods and devices for intracorporeal bonding of implants with thermal energy	2016/08/23
9439642	Methods and devices for utilizing bondable materials	2016/09/13
9463012	Apparatus for guiding and positioning an implant	2016/10/11
9486227	Robotic retractor system	2016/11/08
9545268	Devices and methods for stabilizing tissue and implants	2017/01/17
9579129	Devices and methods for stabilizing tissue and implants	2017/02/28
9585725	Robotic arthroplasty system	2017/03/07
9610073	Methods and devices for intracorporeal bonding of implants with thermal energy	2017/04/04
9629687	Robotic arthroplasty system	2017/04/25
9743963	Methods and devices for trauma welding	2017/08/29
9750496	System for securing a portion of a body	2017/09/05
9770238	Magnetic positioning apparatus	2017/09/26
9808318	Robotic arthroplasty system	2017/11/07
9814453	Deformable fastener system	2017/11/14
9867706	Tissue fastening system	2018/01/16
9877793	Robotic arthroplasty system	2018/01/30
9884451	Method of using ultrasonic vibration to secure body tissue	2018/02/06
9888916	Method and device for securing body tissue	2018/02/13
9962162	Tissue fastener and methods for using same	2018/05/08
9980717	Device and method for securing body tissue	2018/05/29
9980761	Tissue fixation system and method	2018/05/29
9986994	Method and device for securing body tissue	2018/06/05
9999449	Devices and methods for stabilizing tissue and implants	2018/06/19
10058393	Systems and methods for navigation and visualization	2018/08/28
10076377	Fixation systems and methods	2018/09/18
10238378	Tissue fixation system and method	2019/03/26
10265128	Methods of using a robotic spine system	2019/04/23
10368924	Methods and devices for trauma welding	2019/08/06
10368953	Robotic system for fastening layers of body tissue together and method thereof	2019/08/06
10376259	Deformable fastener system	2019/08/13
10390817	Tissue fixation system and method	2019/08/27
10441269	Deformable fastener system	2019/10/15
10517584	Tissue fixation system and method	2019/12/31
10765484	Systems and methods for navigation and visualization	2020/09/08
10813764	Expandable introducer system and methods	2020/10/27
10869728	Robotic surgery	2020/12/22
10932869	Robotic surgery	2021/03/02
10959791	Robotic surgery	2021/03/30
11013542	Tissue fixation system and method	2021/05/25
11129645	Methods of securing a fastener	2021/09/28
11134995	Method and devices for intracorporeal bonding of implants with thermal energy	2021/10/05
11219446	Deformable fastener system	2022/01/11
11246638	Methods and devices for utilizing bondable materials	2022/02/15
11253296	Methods and devices for intracorporeal bonding of implants with thermal energy	2022/02/22
11278331	Method and devices for intracorporeal bonding of implants with thermal energy	2022/03/22
11317974	Systems and methods for navigation and visualization	2022/05/03
11457958	Devices and methods for stabilizing tissue and implants	2022/10/04
11684430	Systems and methods for navigation and visualization	2023/06/27
11744651	Systems and methods for navigation and visualization	2023/09/05
11801044	Tissue fixation system and method	2023/10/31
11992205	Devices and methods for stabilizing tissue and implants	2024/05/28
11998251	Methods and devices for intracorporeal bonding of implants with thermal energy	2024/06/04
12023111	Systems and methods for navigation and visualization	2024/07/02
12096995	Systems and methods for navigation and visualization	2024/09/24
12137898	Tissue fixation system and method	2024/11/12
12232789	Methods and devices for utilizing bondable materials	2025/02/25
12268455	Systems and methods for navigation and visualization	2025/04/08
12364526	Methods and devices for utilizing bondable materials	2025/07/22
12402927	Methods and devices for utilizing bondable materials	2025/09/02

Sofradim Production (67)

Number	Title	Issue Date
10743976	Synthetic prosthesis comprising a knit and a non porous film and method for forming same	2020/08/18
9242026	Biosynthetic implant for soft tissue repair	2016/01/26
9308068	Implant for parastomal hernia	2016/04/12
9445883	Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit	2016/09/20
9499927	Method for producing a prosthesis for reinforcing the abdominal wall	2016/11/22
9526603	Reversible stiffening of light weight mesh	2016/12/27
9554887	Prosthesis comprising a three-dimensional and openworked knit	2017/01/31
9622843	Umbilical hernia prosthesis	2017/04/18
9750837	Haemostatic patch and method of preparation	2017/09/05
9839505	Prosthesis comprising a mesh and a strengthening means	2017/12/12
9867909	Multilayer implants for delivery of therapeutic agents	2018/01/16
9877820	Textile-based prosthesis for treatment of inguinal hernia	2018/01/30
9931198	Prosthesis for supporting a breast structure	2018/04/03
9932695	Prosthetic porous knit	2018/04/03
9980802	Umbilical hernia prosthesis	2018/05/29
10070948	Biosynthetic implant for soft tissue repair	2018/09/11
10080639	Prosthesis for inguinal hernia	2018/09/25
10159555	Packaging for a hernia repair device	2018/12/25
10184032	Method for preparing a chitosan-based matrix comprising a fiber reinforcement member	2019/01/22
10213283	Textile-based prosthesis for laparoscopic surgery	2019/02/26
10327882	Whale concept—folding mesh for TIPP procedure for inguinal hernia	2019/06/25
10342652	Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit	2019/07/09
10363690	Method for preparing a chitosan-based porous layer	2019/07/30
10368971	Implant for parastomal hernia	2019/08/06
10405960	Textile-based prothesis for laparoscopic surgery	2019/09/10
10472750	Prosthesis comprising a three-dimensional and openworked knit	2019/11/12
10549015	Method for preparing an anti-adhesion barrier film	2020/02/04
10646321	Prosthesis for hernia repair	2020/05/12
10653508	Textile-based prosthesis for treatment of inguinal hernia	2020/05/19
10660741	Prosthesis for supporting a breast structure	2020/05/26
10675137	Prosthesis for inguinal hernia repair	2020/06/09
10682215	Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained	2020/06/16
10709538	Umbilical hernia prosthesis	2020/07/14
10745835	Prosthetic porous knit	2020/08/18
10815345	Method for preparing a chitosan-based matrix comprising a fiber reinforcement member	2020/10/27
10865505	Gripping fabric coated with a bioresorbable impenetrable layer	2020/12/15
11039912	Umbilical hernia prosthesis	2021/06/22
11266489	Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit	2022/03/08
11291536	Whale concept-folding mesh for TIPP procedure for inguinal hernia	2022/04/05
11304790	Textile-based prothesis for laparoscopic surgery	2022/04/19
11359313	Prosthetic porous knit	2022/06/14
11389282	Prosthesis for hernia repair	2022/07/19
11439498	Prosthesis for supporting a breast structure	2022/09/13
11471256	Prosthesis for inguinal hernia	2022/10/18
11471257	Implants suitable for soft tissue repair	2022/10/18
11589974	Textile-based prosthesis for treatment of inguinal hernia	2023/02/28
11612472	Prosthesis comprising a three-dimensional and openworked knit	2023/03/28
11622845	Textile-based prothesis for laparoscopic surgery	2023/04/11
11672636	Prosthesis for inguinal hernia repair	2023/06/13
11696819	Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained	2023/07/11
11713526	Prosthetic porous knit	2023/08/01
11903807	Umbilical hernia prosthesis	2024/02/20
11925543	Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit	2024/03/12
11970798	Gripping fabric coated with a bioresorbable impenetrable layer	2024/04/30
12059338	Textile-based prothesis for laparoscopic surgery	2024/08/13
12070534	Method for preparing an anti-adhesion barrier film	2024/08/27
12091788	Prosthetic porous knit	2024/09/17
12161547	Prosthesis for supporting a breast structure	2024/12/10
12257137	Synthetic prosthesis comprising a knit and a non porous film and method for forming same	2025/03/25
12258689	Prosthesis comprising a three-dimensional and openworked knit	2025/03/25
12329626	Umbilical hernia prosthesis	2025/06/17
12392064	Prosthetic porous knit	2025/08/19
12419733	Prosthesis for inguinal hernia	2025/09/23
12496178	Prosthesis for inguinal hernia repair	2025/12/16
12605242	Methods of forming implants suitable for soft tissue repair	2026/04/21
12636139	Prosthesis for hernia repair	2026/05/26
12642637	Bioresorbable knit for hernia repair and method for manufacturing the same	2026/06/02

AccessClosure (26)

Number	Title	Issue Date
7316704	Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture	2008/01/08
7335220	Apparatus and methods for sealing a vascular puncture	2008/02/26
7553319	Auto-injector apparatus and methods for sealing a vascular puncture	2009/06/30
7806856	Apparatus and method for temporary hemostasis	2010/10/05
7985240	Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture	2011/07/26
7993367	Apparatus and methods for sealing a vascular puncture	2011/08/09
8002742	Apparatus and methods for sealing a puncture in tissue	2011/08/23
8029533	Apparatus and methods for sealing a vascular puncture	2011/10/04
8128654	Apparatus and methods for sealing a vascular puncture	2012/03/06
8262693	Apparatus and methods for sealing a vascular puncture	2012/09/11
8348971	Apparatus and methods for facilitating hemostasis within a vascular puncture	2013/01/08
8382797	Methods for sealing a vascular puncture	2013/02/26
8382798	Apparatus for sealing a vascular puncture	2013/02/26
8394122	Apparatus and methods for sealing a vascular puncture	2013/03/12
8617204	Apparatus and methods for sealing a vascular puncture	2013/12/31
8721680	Apparatus and methods for sealing a vascular puncture	2014/05/13
8951283	Apparatus and methods for sealing a vascular puncture	2015/02/10
9289195	Auto-retraction apparatus and methods for sealing a vascular puncture	2016/03/22
9289195	Auto-retraction apparatus and methods for sealing a vascular puncture	2016/03/22
9364206	Apparatus and methods for sealing a vascular puncture	2016/06/14
9386968	Apparatus and methods for sealing a vascular puncture	2016/07/12
9713462	Apparatus and methods for sealing a vascular puncture	2017/07/25
10213191	Apparatus and methods for sealing a vascular puncture	2019/02/26
10499893	Apparatus and methods for sealing a vascular puncture	2019/12/10
10595838	Apparatus and methods for sealing a vascular puncture	2020/03/24
10874384	Apparatus and methods for sealing a vascular puncture	2020/12/29

Access Closure (22)

Number	Title	Issue Date
7331979	Apparatus and methods for sealing a vascular puncture	2008/02/19
9039735	Apparatus and methods for sealing a vascular puncture	2015/05/26
9107645	Apparatus and methods for sealing a puncture in tissue	2015/08/18
9757105	Apparatus and methods for sealing a vascular puncture	2017/09/12
9820728	Apparatus and methods for sealing a vascular puncture	2017/11/21
10149670	Apparatus and methods for sealing a vascular puncture	2018/12/11
10182800	Apparatus and methods for sealing a vascular puncture	2019/01/22
10245012	Apparatus and methods for sealing a vascular puncture	2019/04/02
10314567	Apparatus and methods for sealing a vascular puncture	2019/06/11
10456124	Apparatus and methods for sealing a vascular puncture	2019/10/29
10512455	Apparatus and methods for sealing a vascular puncture	2019/12/24
10806438	Apparatus and methods for sealing a vascular puncture	2020/10/20
11058406	Apparatus and methods for sealing a vascular puncture	2021/07/13
11103224	Apparatus and methods for sealing a vascular puncture	2021/08/31
11272911	Apparatus and method for sealing a vascular puncture	2022/03/15
11534150	Apparatus and methods for sealing a vascular puncture	2022/12/27
11707265	Apparatus and methods for sealing a vascular puncture	2023/07/25
11707266	Apparatus and methods for sealing a vascular puncture	2023/07/25
11925337	Apparatus and methods for sealing a vascular puncture	2024/03/12
12144495	Apparatus and methods for sealing a vascular puncture	2024/11/19
12268378	Apparatus and methods for sealing a vascular puncture	2025/04/08
12433577	Apparatus and methods for sealing a vascular puncture	2025/10/07

Howmedica Osteonics (16)

Number	Title	Issue Date
9402620	Knotless filamentary fixation devices, assemblies and systems and methods of assembly and use	2016/08/02
9445803	Filamentary suture anchor	2016/09/20
9808242	Knotless filament anchor for soft tissue repair	2017/11/07
10123792	Soft tissue fixation devices and methods	2018/11/13
10231744	Flexible ACL instrumentation, kit and method	2019/03/19
10285685	Knotless filamentary fixation devices, assemblies and systems and methods of assembly and use	2019/05/14
10448944	Filamentary fixation device	2019/10/22
10568616	Instruments and methods of soft tissue fixation	2020/02/25
10653410	Soft tissue fixation devices and methods	2020/05/19
11076865	Knotless filament anchor for soft tissue repair	2021/08/03
11364041	Flexible ACL instrumentation, kit and method	2022/06/21
11844508	Filamentary fixation device	2023/12/19
12127748	Knotless filament anchor for soft tissue repair	2024/10/29
12171422	Soft tissue fixation device and methods	2024/12/24
12419655	Flexible ACL instrumentation, kit and method	2025/09/23
12708360	Filamentary fixation device	2026/08/18

Devicor Medical Products (14)

Number	Title	Issue Date
7229417	Methods for marking a biopsy site	2007/06/12
7625397	Methods for defining and marking tissue	2009/12/01
7668582	Biopsy site marker	2010/02/23
8277391	Methods and devices for defining and marking tissue	2012/10/02
8292822	Biopsy localization method and device	2012/10/23
8306602	Biopsy cavity marking device	2012/11/06
8320993	Subcutaneous cavity marking device	2012/11/27
8320994	Biopsy cavity marking device and method	2012/11/27
8600481	Subcutaneous cavity marking device	2013/12/03
9380998	Subcutaneous cavity marking device and method	2016/07/05
9492570	Device and method for safe location and marking of a biopsy cavity	2016/11/15
9669113	Device and method for safe location and marking of a biopsy cavity	2017/06/06
9986974	Biopsy cavity marking device	2018/06/05
10010380	Biopsy localization method and device	2018/07/03

Stout Medical Group, L.P. (13)

Number	Title	Issue Date
8535380	Fixation device and method	2013/09/17
8709042	Expandable support device and method of use	2014/04/29
9259329	Expandable support device and method of use	2016/02/16
9314349	Expandable support device and method of use	2016/04/19
9770339	Expandable support device and method of use	2017/09/26
10285819	Fixation device and method	2019/05/14
10285820	Fixation device and method	2019/05/14
10292828	Fixation device and method	2019/05/21
10758289	Expandable support device and method of use	2020/09/01
10813677	Expandable support device and method of use	2020/10/27
10940014	Fixation device and method	2021/03/09
11051954	Expandable support device and method of use	2021/07/06
11141208	Expandable support device and method of use	2021/10/12

Wright medical Technology (12)

Number	Title	Issue Date
6652887	Bone graft substitute composition	2003/11/25
7211266	Bone graft substitute composition	2007/05/01
7250550	Synthetic bone substitute material	2007/07/31
7291179	Bone graft substitute composition	2007/11/06
7371408	Bone graft substitute composition	2008/05/13
7371409	Bone graft substitute composition	2008/05/13
7371410	Bone graft substitute composition	2008/05/13
7507257	Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects	2009/03/24
7658768	Bone graft substitute composition	2010/02/09
7766972	Synthetic, malleable bone graft substitute material	2010/08/03
8657952	Bone graft substitute composition	2014/02/25
8968465	Bone graft substitute composition	2015/03/03

Arthrex (11)

Number	Title	Issue Date
7959636	Osteochondral repair using plug fashioned from whole distal femur or condyle formed of hydrogel composition	2011/06/14
9700297	Laminated surgical device	2017/07/11
9706986	Knotless suture and tissue securing method	2017/07/18
9770278	Dual tip guide wire	2017/09/26
9775599	Knotless tissue fixation assembly	2017/10/03
9814499	Intramedullary fracture fixation devices and methods	2017/11/14
10052091	Knotless suture or tissue fixation using an implant having a pointed tip	2018/08/21
10537318	Method for knotless fixation of tissue	2020/01/21
10548648	Intramedullary fracture fixation devices and methods	2020/02/04
10709436	Graft fixation using a plug against suture	2020/07/14
11523814	Swivel anchor for knotless fixation of tissue	2022/12/13

Incept (10)

Number	Title	Issue Date
7790192	Apparatus and methods for sealing a vascular puncture	2010/09/07
8470362	Methods for sealing a vascular puncture using a plug including unreactive precursors	2013/06/25
8795709	Superabsorbent, freeze dried hydrogels for medical applications	2014/08/05
8852230	Apparatus and methods for sealing a vascular puncture	2014/10/07
8986730	Methods for sealing a vascular puncture	2015/03/24
9386969	Methods for sealing a vascular puncture	2016/07/12
9463004	Biomaterials for track and puncture closure	2016/10/11
9687216	Methods for sealing a vascular puncture	2017/06/27
10940231	Superabsorbent, freeze dried hydrogels for medical applications	2021/03/09
12350397	Superabsorbent, freeze dried hydrogels for medical applications	2025/07/08

Covidien (5)

Number	Title	Issue Date
9364199	Medical devices	2016/06/14
10016535	Medical devices	2018/07/10
10743976	Synthetic prosthesis comprising a knit and a non porous film and method for forming same	2020/08/18
12064330	Implantable prothesis for minimally invasive hernia repair	2024/08/20
12678273	Implantable prothesis for minimally invasive hernia repair	2026/07/14

AGNOVOS HEALTHCARE, LLC (5)

Number	Title	Issue Date
7754246	Composite bone graft substitute cement and articles produced therefrom	2010/07/13
8025903	Composite bone graft substitute cement and articles produced therefrom	2011/09/27
8685464	Composite bone graft substitute cement and articles produced therefrom	2014/04/01
8685465	Composite bone graft substitute cement and articles produced therefrom	2014/04/01
9180224	Composite bone graft substitute cement and articles produced therefrom	2015/11/10

bonutti skeletal innovations (4)

Number	Title	Issue Date
6955683	Tissue fixation device	2005/10/18
8808329	Apparatus and method for securing a portion of a body	2014/08/19
8814902	Method of securing body tissue	2014/08/26
8845699	Method of securing tissue	2014/09/30

Stryker (4)

Number	Title	Issue Date
9986992	Suture anchor and associated methods of use	2018/06/05
11006945	Suture anchor and associated methods of use	2021/05/18
11331094	Method and apparatus for attaching tissue to bone	2022/05/17
12048427	Method and apparatus for attaching tissue to bone	2024/07/30

SONOMA ORTHOPEDIC PRODUCTS (4)

Number	Title	Issue Date
8961516	Straight intramedullary fracture fixation devices and methods	2015/02/24
9060820	Segmented intramedullary fracture fixation devices and methods	2015/06/23
9155574	Bone fixation device, tools and methods	2015/10/13
9259250	Fracture fixation device, tools and methods	2016/02/16

Warsaw Orthopedic (4)

Number	Title	Issue Date
7052497	Techniques for spinal surgery and attaching constructs to vertebral elements	2006/05/30
7910123	Methods of treating a trauma or disorder of the knee joint by local administration and sustained-delivery of a biological agent	2011/03/22
8012187	Techniques for spinal surgery and attaching constructs to vertebral elements	2011/09/06
8303632	Techniques for spinal surgery and attaching constructs to vertebral elements	2012/11/06

MEDOS INTERNATIONAL SARL (3)

Number	Title	Issue Date
9861410	Methods, devices, and systems for blood flow	2018/01/09
10639085	Methods, devices, and systems for blood flow	2020/05/05
11026729	Methods, devices, and systems for blood flow	2021/06/08

Johnson & Johnson (3)

Number	Title	Issue Date
7622068	Tissue repair device and fabrication thereof	2009/11/24
7641836	Tissue repair device and fabrication thereof	2010/01/05
7862585	Tissue repair device and fabrication thereof	2011/01/04

flexmedex (3)

Number	Title	Issue Date
9050112	Tissue removal device and method	2015/06/09
9149286	Guidance tool and method for use	2015/10/06
10070968	Support device and method for use	2018/09/11

ADVANCED SKELETAL INNOVATIONS LLC (3)

Number	Title	Issue Date
8808329	Apparatus and method for securing a portion of a body	2014/08/19
8814902	Method of securing body tissue	2014/08/26
8845699	Method of securing tissue	2014/09/30

Merz Aesthetics (2)

Number	Title	Issue Date
7968110	Tissue augmentation material and method	2011/06/28
8067027	Tissue augmentation material and method	2011/11/29

Boston Scientific (2)

Number	Title	Issue Date
8292918	Composite plug for arteriotomy closure and method of use	2012/10/23
10363020	Composite plug for arteriotomy closure and method of use	2019/07/30

Sofradim Production SAS (2)

Number	Title	Issue Date
8932619	Dural repair material	2015/01/13
9750846	Bioresorbable and biocompatible compounds for surgical use	2017/09/05

Zimmer (2)

Number	Title	Issue Date
7699853	Method and instruments for positioning humeral component during shoulder arthroplasty	2010/04/20
8545504	Method and instruments for positioning humeral component during shoulder arthroplasty	2013/10/01

parcus medical (2)

Number	Title	Issue Date
11517301	Surgical tool and method of use	2022/12/06
12419630	Surgical tool and method of use	2025/09/23

SIMPARO INC. (2)

Number	Title	Issue Date
11484301	Suture-locking washer for use with a bone anchor, and method for supporting the thumb of a patient after basal joint arthroplasty, and other novel orthopedic apparatus and other novel orthopedic procedures	2022/11/01
12661103	Suture-locking washer for use with a bone anchor, and method for supporting the thumb of a patient after basal joint arthroplasty, and other novel orthopedic apparatus and other novel orthopedic procedures	2026/06/23

WALDEMAR LINK (1)

Number	Title	Issue Date
7553333	Hip prosthesis provided with a shaft inserted into the femur	2009/06/30

BIOVENTUS LLC (1)

Number	Title	Issue Date
9220596	Bone graft materials and methods	2015/12/29

Bolton Medical (1)

Number	Title	Issue Date
6521244	Body filling material	2003/02/18

lifeshield sciences (1)

Number	Title	Issue Date
6994722	Implant having improved fixation to a body lumen and method for implanting the same	2006/02/07

UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (1)

Number	Title	Issue Date
12083246	Composite gels and methods of use thereof	2024/09/10

EVONIK CORPORATION (1)

Number	Title	Issue Date
10669383	Spheronized polymer particles	2020/06/02

RESORBABLE ORTHOPEDIC PRODUCTS, LLC (1)

Number	Title	Issue Date
7074425	Hemostatic compositions and methods	2006/07/11

Terumo (1)

Number	Title	Issue Date
8278397	Medical instrument, medical material, and method for production of the medical instrument and medical material	2012/10/02

PTS (1)

Number	Title	Issue Date
7048963	Layered aligned polymer structures and methods of making same	2006/05/23

convidien (1)

Number	Title	Issue Date
12257137	Synthetic prosthesis comprising a knit and a non porous film and method for forming same	2025/03/25

MERZ NORTH AMERICA, INC. (1)

Number	Title	Issue Date
9352046	Implantation compositions for use in tissue augmentation	2016/05/31

NOVABONE PRODUCTS, (1)

Number	Title	Issue Date
10524916	Resorbable macroporous bioactive glass scaffold and method of manufacture	2020/01/07

biostructures (1)

Number	Title	Issue Date
8551525	Bone graft materials and methods	2013/10/08

arthtrex (1)

Number	Title	Issue Date
10716556	Knotless tissue fixation assembly	2020/07/21

CMC GROUP, INC. (1)

Number	Title	Issue Date
10278692	Sling suspension system for supporting the thumb of a patient after basal joint arthroplasty	2019/05/07

Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
424	423	Emerging	Average	Seminal	Medium	Average	36.8
623	16.11	Emerging	Average	Seminal	Medium High	Average	42.3
623	21.15	Stable	Sustaining	Average	Medium	Average	58.8
623	22.11	Emerging	Average	Seminal	Medium	Average	42.9
623	23.75	Emerging	Average	Seminal	Medium	Average	34.9