Method for treating multiple sclerosis

Overview

Information

Number: 6495579
Application: 09/088546
Filing date: 06/01/1998
Issue date: 12/17/2002
Inventor(s): William L. Hunter

US Classification: 514/365

Citations

Sanofi-aventis (10)

Number	Title	Issue Date
5654449	Taxoids, their preparation and the pharmaceutical compositions which contain them	1997/08/05
5599942	Taxoid intermediates	1997/02/04
5587493	Process for preparing taxoids	1996/12/24
5580998	Process for preparing taxoids	1996/12/03
5580997	Baccatin III derivatives	1996/12/03
5576450	Process for preparing taxoids	1996/11/19
5571917	Taxoid intermediates	1996/11/05
5550261	Taxoids, their preparation and pharmaceutical compositions containing them	1996/08/27
5476954	Process for preparing taxane derivatives, new derivatives obtained and pharmaceutical compositions containing them	1995/12/19
5532388	Taxoids, their preparation and pharmaceutical compositions containing them	1996/07/02

Angiotech International (3)

Number	Title	Issue Date
5716981	Anti-angiogenic compositions and methods of use	1998/02/10
5886026	Anti-angiogenic compositions and methods of use	1999/03/23
5994341	Anti-angiogenic Compositions and methods for the treatment of arthritis	1999/11/30

Merrell Dow Pharmaceuticals (3)

Number	Title	Issue Date
4753965	Method of treating multiple sclerosis with chalcone derivatives	1988/06/28
4863968	Methods of treating gout with chalcone derivatives	1989/09/05
4904697	Controlling the growth of certain tumor tissue with chalcone derivatives	1990/02/27

The Johns Hopkins University (2)

Number	Title	Issue Date
5651986	Controlled local delivery of chemotherapeutic agents for treating solid tumors	1997/07/29
5626862	Controlled local delivery of chemotherapeutic agents for treating solid tumors	1997/05/06

UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (2)

Number	Title	Issue Date
5565478	Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs	1996/10/15
5092885	Peptides with laminin activity	1992/03/03

Children's Medical Center (2)

Number	Title	Issue Date
5567417	Method for inhibiting angiogenesis using heparinase	1996/10/22
4391797	Systems for the controlled release of macromolecules	1983/07/05

NA (2)

Number	Title	Issue Date
5330756	Polyphase fluid extraction process, resulting products and methods of use	1994/07/19
5466455	Polyphase fluid-extraction process, resulting products and methods of use	1995/11/14

ALABAMA AT BIRMINGHAM, UNIVERSITY OF (2)

Number	Title	Issue Date
5733925	Therapeutic inhibitor of vascular smooth muscle cells	1998/03/31
5981568	Therapeutic inhibitor of vascular smooth muscle cells	1999/11/09

Massachusetts Institute Of Technology (2)

Number	Title	Issue Date
5651986	Controlled local delivery of chemotherapeutic agents for treating solid tumors	1997/07/29
5567417	Method for inhibiting angiogenesis using heparinase	1996/10/22

Bristol-Myers Squibb (2)

Number	Title	Issue Date
5635531	3'-aminocarbonyloxy paclitaxels	1997/06/03
5773464	C-10 epoxy taxanes	1998/06/30

HOSTETLER FAMILY TRUST (1)

Number	Title	Issue Date
5411947	Method of converting a drug to an orally available form by covalently bonding a lipid to the drug	1995/05/02

Regents Of The University of Minnesota (1)

Number	Title	Issue Date
5587459	Immunoconjugates comprising tyrosine kinase inhibitors	1996/12/24

PG-TXL (1)

Number	Title	Issue Date
5977163	Water soluble paclitaxel prodrugs	1999/11/02

HOSTETLER, KARL Y. (1)

Number	Title	Issue Date
5411947	Method of converting a drug to an orally available form by covalently bonding a lipid to the drug	1995/05/02

Farmitalia Carlo ERBA S.r.l. (1)

Number	Title	Issue Date
5627207	Arylethenylene compounds which are useful as tyrosine kinase inhibitors	1997/05/06

Chimerix (1)

Number	Title	Issue Date
5411947	Method of converting a drug to an orally available form by covalently bonding a lipid to the drug	1995/05/02

Chemex Pharmaceuticals (1)

Number	Title	Issue Date
5541232	Treatment of multidrug resistant diseases	1996/07/30

Vestar (1)

Number	Title	Issue Date
5484809	Prodrugs for oral administration containing taxol or substituted taxol covalently bound to a phospholipid	1996/01/16

Rhone-Poulenc Rorer (1)

Number	Title	Issue Date
5606083	Process for the preparation of taxane derivatives, new derivatives thus obtained and the compositions which contain them	1997/02/25

SPEED GEL (1)

Number	Title	Issue Date
5654337	Topical formulation for local delivery of a pharmaceutically active agent	1997/08/05

The United States of America as represented by the Department of Health (1)

Number	Title	Issue Date
5616608	Method of treating atherosclerosis or restenosis using microtubule stabilizing agent	1997/04/01

Advanced cardiovascular Systems (1)

Number	Title	Issue Date
5443458	Multilayered biodegradable stent and method of manufacture	1995/08/22

Phanos Technologies (1)

Number	Title	Issue Date
5667764	Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles	1997/09/16

Pfizer (1)

Number	Title	Issue Date
6040306	Method of treating psoriasis, arthritis and reducing the toxicity of cancer chemotherapy	2000/03/21

Procter & Gamble (1)

Number	Title	Issue Date
5565439	Methods of using lysophosphatidic acid for treating hyperproliferative conditions	1996/10/15

Matrix Pharmaceutical (1)

Number	Title	Issue Date
5573781	Methods and compositions for the treatment of a host with a cellular proliferative disease	1996/11/12

Vertex Pharmaceuticals (1)

Number	Title	Issue Date
5620971	Biologically active acylated amino acid derivatives	1997/04/15

COOK MEDICAL TECHNOLOGIES (1)

Number	Title	Issue Date
5873904	Silver implantable medical device	1999/02/23

Abstract

Abstract

Methods and compositions for treating or preventing inflammatory diseases such as psoriasis or multiple sclerosis are provided, comprising the step of delivering to the site of inflammation an anti-microtubule agent, or analogue or derivative thereof.

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Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
514	365	Emerging	Sustaining	Seminal	Medium	Slow	86.7