Methods and compositions for improved articular surgery using collagen

Overview

Information

Number: 7119062
Application: 10/082443
Filing date: 02/22/2002
Issue date: 10/10/2006
Inventor(s): Mark Ray Alvis, Melissa K. C. Brown, Roy C. Fiebiger

US Classification: 514/17.2; 514/18.3; 514/963; 530/356; 604/96.01

Citations

NA (6)

Number	Title	Issue Date
5919473	Methods and devices for delivering opioid analgesics to wounds via a subdermal implant	1999/07/06
6083918	Use of collagen for the treatment of degenerative articular processes	2000/07/04
6165983	Use of collagen for the treatment of degenerative articular processes	2000/12/26
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Cohesion Technologies (3)

Number	Title	Issue Date
4233360	Non-antigenic collagen and articles of manufacture	1980/11/11
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Sumitomo Pharmaceuticals (3)

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SHAHINIAN, LEE, JR (2)

Number	Title	Issue Date
5760077	Topical ophthalmic analgesic preparations for sustained and extended corneal analgesia	1998/06/02
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Angiotech International (2)

Number	Title	Issue Date
5616689	Method of controlling structure stability of collagen fibers produced form solutions or dispersions treated with sodium hydroxide for infectious agent deactivation	1997/04/01
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C.R. Bard (2)

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La Jolla Cancer Research Foundation (1)

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Alfatec Pharma (1)

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5902606	Solid and liquid solutions of sparingly water-soluble medicinal substances	1999/05/11

Universite de Rennes 1 (1)

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Forsyth Dental Infirmary for Children (1)

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4764377	Intra-pocket drug delivery devices for treatment of periodontal diseases	1988/08/16

WEX MEDICAL (1)

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6407088	Method of analgesia	2002/06/18

ALLERGAN (1)

Number	Title	Issue Date
4582640	Injectable cross-linked collagen implant material	1986/04/15

Essential Therapeutics (1)

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6087355	Cephalosporin antibiotics	2000/07/11

Stanford University (1)

Number	Title	Issue Date
3949073	Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution	1976/04/06

Lescarden (1)

Number	Title	Issue Date
3966908	Method of treating degenerative joint afflictions	1976/06/29

University of Medicine and Dentistry of New Jersey (1)

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4703108	Biodegradable matrix and methods for producing same	1987/10/27

Marco Polo Technologies (1)

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TECHNICAL CHEMICALS AND PRODUCTS (1)

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4919939	Periodontal disease treatment system	1990/04/24

Celtrix Pharmaceuticals (1)

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4760131	Wound-healing composition	1988/07/26

Omeros (1)

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6645168	Arthroscopic irrigation solution and method for inhibition of pain and inflammation	2003/11/11

Nutramax Laboratories (1)

Number	Title	Issue Date
4473551	Anti-inflammatory composition	1984/09/25

BioMedicines (1)

Number	Title	Issue Date
5980946	Collagen formulations	1999/11/09

COLLAGEN (1)

Number	Title	Issue Date
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MOSKOVSKII GEOLOGORAZVEDOCHNYI INSTITUT IMENI SERGO ORDJONIKIDZE USSR (1)

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Matrix Pharmaceuticals (1)

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Research Development Foundation (1)

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Centre National de la Recherche Scientifique (1)

Number	Title	Issue Date
6316015	Hyperbactericidal surfaces	2001/11/13

Molecular (1)

Number	Title	Issue Date
4704273	Methods and materials for treatment of rheumatoid arthritis	1987/11/03

ALZA (1)

Number	Title	Issue Date
5540912	Viscous suspensions of controlled-release drug particles	1996/07/30

Pierre Fabre Medicament (1)

Number	Title	Issue Date
4789662	Method for the treatment of periodontal pockets with a composition comprising collagen and an antiseptic or anti-inflammatory substance	1988/12/06

Institut Curie (1)

Number	Title	Issue Date
6316015	Hyperbactericidal surfaces	2001/11/13

Deutsche Gelatine-Fabriken Stoess & Co. (1)

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4804745	Agents for the treatment of arthroses	1989/02/14

kci usa (1)

Number	Title	Issue Date
5766631	Wound implant materials	1998/06/16

Abstract

Abstract

The invention provides methods for treating post-surgical articular or incisional pain and/or discomfort in a patient. The invention further provides improved surgical methods and controlled release formulations for treating an articular injury of a joint in a patient, in which a collagen formulation is used in conjunction with a surgical procedure to treat the articular injury or the side effects of the surgical procedure. Collagen formulations of the invention and their use, in addition to the surgical procedure, may provide at least one or more of the following benefits: reduced patient pain, shortened recovery time and/or improved joint condition (including treatment of the underlying articular injury). Moreover, the methods and compositions of the invention can be used in conjunction with essentially any surgical procedure used to treat an articular injury. The invention further provides compositions and methods for treating post-surgical articular or incisional pain in a patient as well as a catheter for use in the methods of the invention.

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Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
514	17.2	Stable	Sustaining	Average	Medium	Slow	82.6
514	18.3	Emerging	Sustaining	Seminal	Medium	Slow	83.7
514	963	Stable	Sustaining	Average	Medium	Slow	90.4
530	356	Stable	Sustaining	Average	Medium	Slow	86.8
604	96.01	Emerging	Average	Average	Medium High	Slow	78.8