| Number | Title | Issue Date |
|---|---|---|
| 5614587 | Collagen-based bioadhesive compositions | 1997/03/25 |
| 5874500 | Crosslinked polymer compositions and methods for their use | 1999/02/23 |
| 6312725 | Rapid gelling biocompatible polymer composition | 2001/11/06 |
| 6495127 | Compositions and systems for forming high strength medical sealants, and associated methods of preparation and use | 2002/12/17 |
| Number | Title | Issue Date |
|---|---|---|
| 5290552 | Surgical adhesive material | 1994/03/01 |
| 5693341 | Affinity bound collagen matrices for the delivery of biologically active agents | 1997/12/02 |
| 5752974 | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body | 1998/05/19 |
| Number | Title | Issue Date |
|---|---|---|
| 6096309 | Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof | 2000/08/01 |
| Number | Title | Issue Date |
|---|---|---|
| 6310036 | High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces | 2001/10/30 |
| Number | Title | Issue Date |
|---|---|---|
| 6458147 | Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue | 2002/10/01 |
| Number | Title | Issue Date |
|---|---|---|
| 6149581 | Device and method for access to the colon and small bowel of a patient | 2000/11/21 |
| Number | Title | Issue Date |
|---|---|---|
| 8880185 | Renal denervation and stimulation employing wireless vascular energy transfer arrangement | 2014/11/04 |
| 8951251 | Ostial renal nerve ablation | 2015/02/10 |
| 8974451 | Renal nerve ablation using conductive fluid jet and RF energy | 2015/03/10 |
| 9023034 | Renal ablation electrode with force-activatable conduction apparatus | 2015/05/05 |
| 9028485 | Self-expanding cooling electrode for renal nerve ablation | 2015/05/12 |
| 9079000 | Integrated crossing balloon catheter | 2015/07/14 |
| 9089350 | Renal denervation catheter with RF electrode and integral contrast dye injection arrangement | 2015/07/28 |
| 9119600 | Device and methods for renal nerve modulation monitoring | 2015/09/01 |
| 9119632 | Deflectable renal nerve ablation catheter | 2015/09/01 |
| 9155589 | Sequential activation RF electrode set for renal nerve ablation | 2015/10/13 |
| 9162046 | Deflectable medical devices | 2015/10/20 |
| 9173696 | Self-positioning electrode system and method for renal nerve modulation | 2015/11/03 |
| 9186209 | Nerve modulation system having helical guide | 2015/11/17 |
| 9186210 | Medical devices including ablation electrodes | 2015/11/17 |
| 9186211 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2015/11/17 |
| 9192435 | Renal denervation catheter with cooled RF electrode | 2015/11/24 |
| 9192790 | Focused ultrasonic renal denervation | 2015/11/24 |
| 9220558 | RF renal denervation catheter with multiple independent electrodes | 2015/12/29 |
| 9220561 | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury | 2015/12/29 |
| 9297845 | Medical devices and methods for treatment of hypertension that utilize impedance compensation | 2016/03/29 |
| 9326751 | Catheter guidance of external energy for renal denervation | 2016/05/03 |
| 9358365 | Precision electrode movement control for renal nerve ablation | 2016/06/07 |
| 9364284 | Method of making an off-wall spacer cage | 2016/06/14 |
| 9408661 | RF electrodes on multiple flexible wires for renal nerve ablation | 2016/08/09 |
| 9420955 | Intravascular temperature monitoring system and method | 2016/08/23 |
| 9433760 | Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements | 2016/09/06 |
| 9463062 | Cooled conductive balloon RF catheter for renal nerve ablation | 2016/10/11 |
| 9579030 | Percutaneous devices and methods to visualize, target and ablate nerves | 2017/02/28 |
| 9649156 | Bipolar off-wall electrode device for renal nerve ablation | 2017/05/16 |
| 9668811 | Minimally invasive access for renal nerve ablation | 2017/06/06 |
| 9687166 | High resolution cardiac mapping electrode array catheter | 2017/06/27 |
| 9693821 | Medical devices for modulating nerves | 2017/07/04 |
| 9707036 | Devices and methods for nerve modulation using localized indifferent electrodes | 2017/07/18 |
| 9713730 | Apparatus and method for treatment of in-stent restenosis | 2017/07/25 |
| 9770606 | Ultrasound ablation catheter with cooling infusion and centering basket | 2017/09/26 |
| 9808300 | Control of arterial smooth muscle tone | 2017/11/07 |
| 9808311 | Deflectable medical devices | 2017/11/07 |
| 9827039 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2017/11/28 |
| 9833283 | Medical devices for renal nerve ablation | 2017/12/05 |
| 9848946 | Self-expanding cooling electrode for renal nerve ablation | 2017/12/26 |
| 9895194 | Radio frequency (RF) balloon catheter having flushing and cooling capability | 2018/02/20 |
| 9907609 | Alternative placement of thermal sensors on bipolar electrode | 2018/03/06 |
| 9925001 | Spiral bipolar electrode renal denervation balloon | 2018/03/27 |
| 9943365 | Renal denervation balloon catheter with ride along electrode support | 2018/04/17 |
| 9956033 | Medical devices for modulating nerves | 2018/05/01 |
| 9962223 | Medical device balloon | 2018/05/08 |
| 10022182 | Medical devices for renal nerve ablation having rotatable shafts | 2018/07/17 |
| 10085799 | Off-wall electrode device and methods for nerve modulation | 2018/10/02 |
| 10265122 | Nerve ablation devices and related methods of use | 2019/04/23 |
| 10271898 | Embedded thermocouple in denervation flex circuit | 2019/04/30 |
| 10321946 | Renal nerve modulation devices with weeping RF ablation balloons | 2019/06/18 |
| 10342609 | Medical devices for renal nerve ablation | 2019/07/09 |
| 10398464 | System for nerve modulation and innocuous thermal gradient nerve block | 2019/09/03 |
| 10413356 | System for inducing desirable temperature effects on body tissue | 2019/09/17 |
| 10413357 | Medical device with stretchable electrode assemblies | 2019/09/17 |
| 10549127 | Self-cooling ultrasound ablation catheter | 2020/02/04 |
| 10660698 | Devices and methods for nerve modulation | 2020/05/26 |
| 10660703 | Renal nerve modulation devices | 2020/05/26 |
| 10695124 | Renal nerve ablation catheter having twist balloon | 2020/06/30 |
| 10722300 | Flexible circuit having improved adhesion to a renal nerve modulation balloon | 2020/07/28 |
| 10835305 | Renal nerve modulation devices and methods | 2020/11/17 |
| 10945786 | Balloon catheters with flexible conducting wires and related methods of use and manufacture | 2021/03/16 |
| 10952790 | Ablation balloon with vapor deposited cover layer | 2021/03/23 |
| 11000679 | Balloon protection and rewrapping devices and related methods of use | 2021/05/11 |
| 11202671 | Tear resistant flex circuit assembly | 2021/12/21 |
| 11246654 | Flexible renal nerve ablation devices and related methods of use and manufacture | 2022/02/15 |
| 12161392 | System for inducing desirable temperature effects on body tissue | 2024/12/10 |
| 12167889 | Flexible circuit having improved adhesion to a renal nerve modulation balloon | 2024/12/17 |
| 12558576 | System for nerve modulation and innocuous thermal gradient nerve block | 2026/02/24 |
| Number | Title | Issue Date |
|---|---|---|
| 9486270 | Methods and apparatus for bilateral renal neuromodulation | 2016/11/08 |
| 9636174 | Methods for therapeutic renal neuromodulation | 2017/05/02 |
| 9713483 | Catheters and related devices for forming passageways between blood vessels or other anatomical structures | 2017/07/25 |
| 9757193 | Balloon catheter apparatus for renal neuromodulation | 2017/09/12 |
| 9814873 | Methods and apparatus for bilateral renal neuromodulation | 2017/11/14 |
| 9827040 | Methods and apparatus for intravascularly-induced neuromodulation | 2017/11/28 |
| 9827041 | Balloon catheter apparatuses for renal denervation | 2017/11/28 |
| 9968611 | Methods and devices for renal nerve blocking | 2018/05/15 |
| 10034708 | Methods and apparatus for thermally-induced renal neuromodulation | 2018/07/31 |
| 10105180 | Methods and apparatus for intravascularly-induced neuromodulation | 2018/10/23 |
| 10124195 | Methods for thermally-induced renal neuromodulation | 2018/11/13 |
| 10130792 | Methods for therapeutic renal neuromodulation using neuromodulatory agents or drugs | 2018/11/20 |
| 10179027 | Catheter apparatuses having expandable baskets for renal neuromodulation and associated systems and methods | 2019/01/15 |
| 10179235 | Methods and apparatus for bilateral renal neuromodulation | 2019/01/15 |
| 10293190 | Thermally-induced renal neuromodulation and associated systems and methods | 2019/05/21 |
| 10335280 | Method for ablating target tissue of a patient | 2019/07/02 |
| 10376311 | Methods and apparatus for intravascularly-induced neuromodulation | 2019/08/13 |
| 10376516 | Methods and devices for renal nerve blocking | 2019/08/13 |
| 10420606 | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen | 2019/09/24 |
| 10441356 | Methods for renal neuromodulation via neuromodulatory agents | 2019/10/15 |
| 10588682 | Apparatus and methods related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls | 2020/03/17 |
| 10589130 | Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions | 2020/03/17 |
| 10709490 | Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods | 2020/07/14 |
| 10850091 | Methods and apparatus for bilateral renal neuromodulation | 2020/12/01 |
| 11116561 | Devices, agents, and associated methods for selective modulation of renal nerves | 2021/09/14 |
| Number | Title | Issue Date |
|---|---|---|
| 8939970 | Tuned RF energy and electrical tissue characterization for selective treatment of target tissues | 2015/01/27 |
| 9028472 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2015/05/12 |
| 9037259 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2015/05/19 |
| 9072902 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2015/07/07 |
| 9125666 | Selectable eccentric remodeling and/or ablation of atherosclerotic material | 2015/09/08 |
| 9125667 | System for inducing desirable temperature effects on body tissue | 2015/09/08 |
| 9174050 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2015/11/03 |
| 9277955 | Power generating and control apparatus for the treatment of tissue | 2016/03/08 |
| 9327100 | Selective drug delivery in a lumen | 2016/05/03 |
| 9402684 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2016/08/02 |
| 9486355 | Selective accumulation of energy with or without knowledge of tissue topography | 2016/11/08 |
| 9510901 | Selectable eccentric remodeling and/or ablation | 2016/12/06 |
| 9592386 | Methods and apparatuses for remodeling tissue of or adjacent to a body passage | 2017/03/14 |
| 9974607 | Inducing desirable temperature effects on body tissue | 2018/05/22 |
| 10188457 | Selectable eccentric remodeling and/or ablation | 2019/01/29 |
| Number | Title | Issue Date |
|---|---|---|
| 8968210 | Device for needle biopsy with integrated needle protection | 2015/03/03 |
| 9186128 | Needle biopsy device | 2015/11/17 |
| 9332973 | Needle biopsy device with exchangeable needle and integrated needle protection | 2016/05/10 |
| 9782565 | Endoscopic ultrasound-guided biliary access system | 2017/10/10 |
| 9913630 | Device for needle biopsy with integrated needle protection | 2018/03/13 |
| 9919144 | Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery | 2018/03/20 |
| 10076316 | Needle biopsy device | 2018/09/18 |
| 10888689 | Endoscopic ultrasound-guided biliary access system | 2021/01/12 |
| 11039816 | Needle biopsy device with exchangeable needle and integrated needle protection | 2021/06/22 |
| 11298113 | Device for needle biopsy with integrated needle protection | 2022/04/12 |
| Number | Title | Issue Date |
|---|---|---|
| 9670258 | Positive modulator of bone morphogenic protein-2 | 2017/06/06 |
| 10246499 | Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2019/04/02 |
| 11078244 | Composition and method for delivery of BMP-2 amplifler/co-activator for enhancement of osteogenesis | 2021/08/03 |
| 7981862 | Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2011/07/19 |
| 8227411 | FGF growth factor analogs | 2012/07/24 |
| 8796212 | Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2014/08/05 |
| 10174088 | Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2019/01/08 |
| 12173040 | Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2024/12/24 |
| Number | Title | Issue Date |
|---|---|---|
| 7700819 | Biocompatible wound dressing | 2010/04/20 |
| 7763769 | Biocompatible wound dressing | 2010/07/27 |
| 8084664 | Biocompatible wound dressing | 2011/12/27 |
| 8163974 | Biocompatible wound dressing | 2012/04/24 |
| 8735644 | Biocompatible wound dressing | 2014/05/27 |
| Number | Title | Issue Date |
|---|---|---|
| 7354602 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use | 2008/04/08 |
| 7354603 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use | 2008/04/08 |
| 7357948 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use | 2008/04/15 |
| 7585521 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use | 2009/09/08 |
| Number | Title | Issue Date |
|---|---|---|
| 8968210 | Device for needle biopsy with integrated needle protection | 2015/03/03 |
| 9186128 | Needle biopsy device | 2015/11/17 |
| 9332973 | Needle biopsy device with exchangeable needle and integrated needle protection | 2016/05/10 |
| 9913630 | Device for needle biopsy with integrated needle protection | 2018/03/13 |
| Number | Title | Issue Date |
|---|---|---|
| 8163717 | Dual chain synthetic heparin-binding growth factor analogs | 2012/04/24 |
| 9670258 | Positive modulator of bone morphogenic protein-2 | 2017/06/06 |
| 10246499 | Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis | 2019/04/02 |
| 11078244 | Composition and method for delivery of BMP-2 amplifler/co-activator for enhancement of osteogenesis | 2021/08/03 |
| Number | Title | Issue Date |
|---|---|---|
| 9414967 | Composition, preparation, and use of chitosan shards for biomedical applications | 2016/08/16 |
| 9226988 | Chitosan-based hemostatic textile | 2016/01/05 |
| 9259357 | Composition, preparation, and use of chitosan shards for biomedical applications | 2016/02/16 |
| Number | Title | Issue Date |
|---|---|---|
| 9060761 | Catheter-focused magnetic field induced renal nerve ablation | 2015/06/23 |
| 9084609 | Spiral balloon catheter for renal nerve ablation | 2015/07/21 |
| Number | Title | Issue Date |
|---|---|---|
| 8088060 | Progenitor endothelial cell capturing with a drug eluting implantable medical device | 2012/01/03 |
| 9522217 | Medical device with coating for capturing genetically-altered cells and methods for using same | 2016/12/20 |
| Number | Title | Issue Date |
|---|---|---|
| 10350004 | Intravascular treatment catheters | 2019/07/16 |
| 11272982 | Intravascular treatment catheters | 2022/03/15 |
| Number | Title | Issue Date |
|---|---|---|
| 9414967 | Composition, preparation, and use of chitosan shards for biomedical applications | 2016/08/16 |
| 9259357 | Composition, preparation, and use of chitosan shards for biomedical applications | 2016/02/16 |
| Number | Title | Issue Date |
|---|---|---|
| 7468210 | Cross-linked heparin coatings and methods | 2008/12/23 |
| 8101570 | Single branch heparin-binding growth factor analogs | 2012/01/24 |
| Number | Title | Issue Date |
|---|---|---|
| 11213610 | Biopolymer scaffold implants and methods for their production | 2022/01/04 |
| 12201748 | Biopolymer scaffold implants and methods for their production | 2025/01/21 |
| Number | Title | Issue Date |
|---|---|---|
| 9265969 | Methods for modulating cell function | 2016/02/23 |
| Number | Title | Issue Date |
|---|---|---|
| 12090065 | System and method for treatment of bone | 2024/09/17 |
| Number | Title | Issue Date |
|---|---|---|
| 7570986 | Teniae coli guided navigation and registration for virtual colonoscopy | 2009/08/04 |
| Number | Title | Issue Date |
|---|---|---|
| 12290612 | Aligned fiber and method of use thereof | 2025/05/06 |
| Number | Title | Issue Date |
|---|---|---|
| 7820172 | Laminin-derived multi-domain peptides | 2010/10/26 |
| Number | Title | Issue Date |
|---|---|---|
| 8865964 | Biomaterials, their preparation by electrospinning and their use in the biomedical and surgical field | 2014/10/21 |
| Number | Title | Issue Date |
|---|---|---|
| 9750532 | Access needles and stylet assemblies | 2017/09/05 |
| Number | Title | Issue Date |
|---|---|---|
| 10213252 | Inducing desirable temperature effects on body tissue | 2019/02/26 |
| Number | Title | Issue Date |
|---|---|---|
| 10611810 | Positive modulator of bone morphogenic protein-2 | 2020/04/07 |
| Number | Title | Issue Date |
|---|---|---|
| 9414967 | Composition, preparation, and use of chitosan shards for biomedical applications | 2016/08/16 |
| Number | Title | Issue Date |
|---|---|---|
| 9504575 | 3-dimensional silk hydroxyapatite compositions | 2016/11/29 |
| Number | Title | Issue Date |
|---|---|---|
| 10792338 | Erythropoietin and fibronectin compositions for therapeutic and cosmetic applications | 2020/10/06 |
| Class | Subclass | Type | Reference Factor | Citation Factor | Strength | Grant time | Early grant (%) |
|---|---|---|---|---|---|---|---|
| 424 | 85.1 | Emerging | Sustaining | Seminal | Medium | Average | 25.8 |
| 435 | 69.5 | Emerging | Sustaining | Seminal | Medium | Rapid | 22.0 |
| 514 | 11.3 | Stable | Sustaining | Average | Medium | Average | 33.1 |
| 514 | 13.2 | Stable | Sustaining | Seminal | Medium | Average | 31.7 |
| 514 | 13.6 | Stable | Sustaining | Average | Medium | Average | 28.5 |
| 514 | 2.3 | Stable | Sustaining | Seminal | Medium | Average | 29.4 |
| 530 | 353 | Emerging | Sustaining | Seminal | Medium | Average | 30.1 |