Medicated stent having multi-layer polymer coating

Overview

Information

Number: 7771468
Application: 10/662877
Filing date: 09/16/2003
Issue date: 08/10/2010
Inventor(s): Richard J. Whitbourne, Alexandra M. Chamberlain, Daniel G. Hullihen, Scott F. Rosebrough, Mildred Calistri-Yeh

US Classification: 623/1.42; 623/1.44

Citations

ALABAMA AT BIRMINGHAM, UNIVERSITY OF (8)

Number	Title	Issue Date
6268390	Therapeutic inhibitor of vascular smooth muscle cells	2001/07/31
5733925	Therapeutic inhibitor of vascular smooth muscle cells	1998/03/31
6074659	Therapeutic inhibitor of vascular smooth muscle cells	2000/06/13
6599928	Therapeutic inhibitor of vascular smooth muscle cells	2003/07/29
6515009	Therapeutic inhibitor of vascular smooth muscle cells	2003/02/04
6491938	Therapeutic inhibitor of vascular smooth muscle cells	2002/12/10
6171609	Therapeutic inhibitor of vascular smooth muscle cells	2001/01/09
6306421	Therapeutic inhibitor of vascular smooth muscle cells	2001/10/23

Advanced cardiovascular Systems (7)

Number	Title	Issue Date
6251136	Method of layering a three-coated stent using pharmacological and polymeric agents	2001/06/26
6395326	Apparatus and method for depositing a coating onto a surface of a prosthesis	2002/05/28
6254632	Implantable medical device having protruding surface structures for drug delivery and cover attachment	2001/07/03
5707385	Drug loaded elastic membrane and method for delivery	1998/01/13
6616765	Apparatus and method for depositing a coating onto a surface of a prosthesis	2003/09/09
5843172	Porous medicated stent	1998/12/01
6663662	Diffusion barrier layer for implantable devices	2003/12/16

Boston Scientific (6)

Number	Title	Issue Date
7052488	Implantable drug delivery device	2006/05/30
7041130	Stent for controlled release of drug	2006/05/09
5972027	Porous stent drug delivery system	1999/10/26
6197051	Polycarbonate-polyurethane dispersions for thromobo-resistant coatings	2001/03/06
6783543	Intravascular stent with increasing coating retaining capacity	2004/08/31
6258121	Stent coating	2001/07/10

SURGICAL SPECIALTIES (6)

Number	Title	Issue Date
6368611	Anti-infective covering for percutaneous and vascular access device and coating method	2002/04/09
5997517	Bonding layers for medical device surface coatings	1999/12/07
6306176	Bonding layers for medical device surface coatings	2001/10/23
6086547	Wire for medical use coated with polyether sulphone and a copolymer	2000/07/11
5800412	Hydrophilic coatings with hydrating agents	1998/09/01
6110483	Adherent, flexible hydrogel and medicated coatings	2000/08/29

Angiotech International (5)

Number	Title	Issue Date
5331027	Lubricious hydrophilic coating, resistant to wet abrasion	1994/07/19
5525348	Coating compositions comprising pharmaceutical agents	1996/06/11
5716981	Anti-angiogenic compositions and methods of use	1998/02/10
5069899	Anti-thrombogenic, anti-microbial compositions containing heparin	1991/12/03
5001009	Lubricious hydrophilic composite coated on substrates	1991/03/19

Cordis (4)

Number	Title	Issue Date
6153252	Process for coating stents	2000/11/28
5882335	Retrievable drug delivery stent	1999/03/16
4733665	Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft	1988/03/29
6273913	Modified stent useful for delivery of drugs along stent strut	2001/08/14

COOK MEDICAL TECHNOLOGIES (4)

Number	Title	Issue Date
6096070	Coated implantable medical device	2000/08/01
5873904	Silver implantable medical device	1999/02/23
5609629	Coated implantable medical device	1997/03/11
5380299	Thrombolytic treated intravascular medical device	1995/01/10

Medtronic (3)

Number	Title	Issue Date
5851217	Intralumenal drug eluting prosthesis	1998/12/22
5837008	Intravascular stent and method	1998/11/17
4886062	Intravascular radially expandable stent and method of implant	1989/12/12

ALZA (2)

Number	Title	Issue Date
6071305	Directional drug delivery stent and method of use	2000/06/06
4723957	System for delivering drug with enhanced bioacceptability	1988/02/09

IPXMEDICAL, LLC (2)

Number	Title	Issue Date
6515016	Composition and methods of paclitaxel for treating psoriasis	2003/02/04
6515016	Composition and methods of paclitaxel for treating psoriasis	2003/02/04

MicroChips (2)

Number	Title	Issue Date
6656162	Implantable drug delivery stents	2003/12/02
6491666	Microfabricated devices for the delivery of molecules into a carrier fluid	2002/12/10

Target Therapeutics (1)

Number	Title	Issue Date
5980550	Water-soluble coating for bioactive vasoocclusive devices	1999/11/09

Scimed Life Systems (1)

Number	Title	Issue Date
6335029	Polymeric coatings for controlled delivery of active agents	2002/01/01

Tyndale Plains-Hunter (1)

Number	Title	Issue Date
5962620	Hydrophicic and hydrophobic polyether polyurethanes and uses therefor	1999/10/05

PG-TXL (1)

Number	Title	Issue Date
5977163	Water soluble paclitaxel prodrugs	1999/11/02

Massachusetts Institute Of Technology (1)

Number	Title	Issue Date
5797898	Microchip drug delivery devices	1998/08/25

ADVANCED LASER APPLICATIONS (1)

Number	Title	Issue Date
7135039	Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof	2006/11/14

BIOADVANCES, (1)

Number	Title	Issue Date
5840329	Pulsatile drug delivery system	1998/11/24

Focal (1)

Number	Title	Issue Date
5779673	Devices and methods for application of intraluminal photopolymerized gels	1998/07/14

Emory University (1)

Number	Title	Issue Date
5523092	Device for local drug delivery and methods for using the same	1996/06/04

SurModics (1)

Number	Title	Issue Date
6344035	Bioactive agent release coating	2002/02/05

BTG International (1)

Number	Title	Issue Date
5294448	Delayed release formulations	1994/03/15

cid s p a (1)

Number	Title	Issue Date
6699281	Angioplasty stents	2004/03/02

DOW CHEMICAL (1)

Number	Title	Issue Date
5620738	Non-reactive lubicious coating process	1997/04/15

NA (1)

Number	Title	Issue Date
6273908	Stents	2001/08/14

Children's Medical Center (1)

Number	Title	Issue Date
4391797	Systems for the controlled release of macromolecules	1983/07/05

HEALTH AND HUMAN SERVICES, UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY (1)

Number	Title	Issue Date
6403635	Method of treating atherosclerosis or restenosis using microtubule stabilizing agent	2002/06/11

Cook (1)

Number	Title	Issue Date
4800882	Endovascular stent and delivery system	1989/01/31

C.R. Bard (1)

Number	Title	Issue Date
4531933	Helical ureteral stent	1985/07/30

Dexcel Pharma Technologies (1)

Number	Title	Issue Date
5866619	Colonic drug delivery system	1999/02/02

Abstract

This invention relates to stents having medicated multi-layer hybrid polymer coatings, useful for the treatment of stenosed vasculature or other body passages.

Assignees with Similar Patents

Medtronic (15)

Number	Title
101468625	Reflowed Drug-Polymer Coated Stent and Method Thereof
101644519	Drug-Polymer Coated Stent
101073532	Reflowed drug-polymer coated stent and method thereof
102531098	Drug-Polymer Coated Stent
5679400	Intravascular stent and method
100855745	Medical devices and compositions for delivering biophosphonates to anatomical sites at risk for vascular disease
100710916	Active agent delivery system including a hydrophilic polymer, medical device, and method
100708167	Reflowed drug-polymer coated stent and method thereof
7744645	Laminated drug-polymer coated stent with dipped and cured layers
7704545	Drug-polymer coated stent
7575632	Reflowed drug-polymer coated stent and method thereof
7163555	Drug-eluting stent for controlled drug delivery
6979348	Reflowed drug-polymer coated stent and method thereof
100639902	Drug-eluting stent for controlled drug delivery
100698632	Drug-polymer coated stent with polysulfone and styrenic block copolymer

Advanced cardiovascular Systems (13)

Number	Title
7014913	Rate-reducing membrane for release of an agent
7022334	Therapeutic composition and a method of coating implantable medical devices
7255891	Method for coating implantable medical devices
7396539	Stent coatings with engineered drug release rate
7396541	Heparin prodrugs and drug delivery stents formed therefrom
102543015	BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF
102475788	BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF
7481835	Encapsulated covered stent
6824559	Ethylene-carboxyl copolymers as drug delivery matrices
7648727	Methods for manufacturing a coated stent-balloon assembly
101184427	Heparin prodrugs and drug delivery stents formed therefrom
101455573	Polymeric coating for reducing the rate of release of a therapeutic substance from a stent
101560922	Method for coating implantable medical devices

NA (7)

Number	Title
102218509	METHOD FOR ELECTROSTATIC COATING OF A MEDICAL DEVICE
102271795	COATING FOR A MEDICAL DEVICE HAVING AN ANTI-THROMBOTIC CONJUGATE
102408334	COATED STENT AND METHOD OF MAKING THE SAME
102100051	Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings
102562955	ADHESION PROMOTING TEMPORARY MASK FOR COATED SURFACES
102625906	POLYMER FOR CREATING HEMOCOMPATIBLE SURFACE
102643989	ADHESION PROMOTING TEMPORARY MASK FOR COATED SURFACES

IPXMEDICAL, LLC (6)

Number	Title
8287590	Medicated stent having multi-layer polymer coating
8287590	Medicated stent having multi-layer polymer coating
8101200	Targeted therapeutic agent release devices and methods of making and using the same
8101200	Targeted therapeutic agent release devices and methods of making and using the same
7771468	Medicated stent having multi-layer polymer coating
7771468	Medicated stent having multi-layer polymer coating

Boston Scientific (6)

Number	Title
101857019	STENT WITH UNCONNECTED STENT SEGMENTS
8431149	Coated medical devices for abluminal drug delivery
6306166	Loading and release of water-insoluble drugs
102834635	INERT HEAT TREATMENT TO IMPROVE COATING ADHESION AND PRODUCT PERFORMANCE CHARACTERISTICS FOR BIODEGRADEABLE COATINGS
103016826	LOADING AND RELEASE OF WATER-INSOLUBLE DRUGS
103187562	LOADING AND RELEASE OF WATER-INSOLUBLE DRUGS

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Tech Analysis

Class	Subclass	Type	Reference Factor	Citation Factor	Strength	Grant time	Early grant (%)
623	1.42	Emerging	Average	Average	Medium	Slow	89.8
623	1.44	Stable	Sustaining	Average	Medium Low	Slow	92.0