Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
Overview
Citations
- Nektar Therapeutics (1)
-
| Number |
Title |
Issue Date |
| 6908963 |
Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith |
2005/06/21 |
Abstract
Multifunctional compounds are provided that readily crosslink in situ to provide crosslinked biomaterials. The multifunctional compounds contain a single component having at least three reactive functional groups thereon, with the functional groups selected so as to be non-reactive in an initial environment and inter-reactive in a modified environment. Reaction of a plurality of the multifunctional compounds results in a three-dimensional crosslinked matrix. In one embodiment, a first functional group is nucleophilic, a second functional group is electrophilic, and at least one additional functional group is nucleophilic or electrophilic. Methods for preparing and using the multifunctional compounds, and kits including the multifunctional compounds are also provided. Exemplary uses for the multifunctional compounds include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery or injury.
Assignees with Similar Patents
Referenced by
- Halliburton (6)
-
| Number |
Title |
Issue Date |
| 9260343 |
Set-delayed cement compositions comprising pumice and associated methods |
2016/02/16 |
| 9790132 |
Set-delayed cement compositions comprising pumice and associated methods |
2017/10/17 |
| 10195764 |
Set-delayed cement compositions comprising pumice and associated methods |
2019/02/05 |
| 10202751 |
Set-delayed cement compositions comprising pumice and associated methods |
2019/02/12 |
| 10221095 |
Set-delayed cement compositions comprising pumice and associated methods |
2019/03/05 |
| 10626057 |
Set-delayed cement compositions comprising pumice and associated methods |
2020/04/21 |
- Angiotech International (2)
-
| Number |
Title |
Issue Date |
| 8486437 |
Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use |
2013/07/16 |
| 9353218 |
Kit for multifunctional compounds forming crosslinked biomaterials |
2016/05/31 |
- Elkay Manufacturing (2)
-
| Number |
Title |
Issue Date |
| 11339045 |
Flavor and additive delivery systems and methods for beverage dispensers |
2022/05/24 |
| 11697578 |
Flavor and additive delivery systems and methods for beverage dispensers |
2023/07/11 |
- englewood lab (2)
-
| Number |
Title |
Issue Date |
| 9226890 |
Polysilicone base for scar treatment |
2016/01/05 |
| 9415002 |
Polysilicone base for scar treatment |
2016/08/16 |
- Smith & Nephew (1)
-
| Number |
Title |
Issue Date |
| 10675392 |
Wound management |
2020/06/09 |
- University of Notre Dame Du Lac (1)
-
| Number |
Title |
Issue Date |
| 9550012 |
Tissue scaffolds having bone growth factors |
2017/01/24 |
Tech Analysis
| Class |
Subclass |
Type |
Reference Factor |
Citation Factor |
Strength |
Grant time |
Early grant (%) |
|
424
|
423
|
Emerging |
Novel |
Average |
Medium |
Slow |
93.1 |